1. Elevated inflammatory indicators from routine complete blood cell counts may be independently associated with higher all-cause mortality in patients with rheumatoid arthritis.
2. The study included 1314 patients with rheumatoid arthritis, and elevated levels of systemic inflammatory response index (SIRI), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) were associated with increased mortality.
3. After adjusting for covariates, elevated SIRI, NLR, and MLR remained independently associated with increased mortality.
4. In fully adjusted models, the highest tertile of SIRI, NLR, and MLR was associated with a higher hazard ratio compared to their lowest tertiles.
5. SIRI, NLR, and MLR were more common in patients aged 60 years and older, male patients, and those with hypertension.
6. Complete blood cell count–derived markers such as SIRI, NLR, and MLR may serve as accessible prognostic indicators for long-term mortality risk in rheumatoid arthritis.

Do CBC Ratios Predict RA Mortality? | Conexiant