May 08, 2026

Tofacitinib vs Adalimumab Findings Require Caution in RA

Meta-analysis favored tofacitinib for some rheumatoid arthritis outcomes, but high heterogeneity, dose-dependent effects, and JAK inhibitor safety concerns complicate interpretation.

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May 08, 2026

Lung Disease Complicates RA Care

Patients with chronic lung disease had numerically lower remission rates and substantially more serious adverse events in a 5-year Japanese registry study of late-onset rheumatoid arthritis.

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May 06, 2026

Deep Remission Tied to RA Control

At 5 years, 63% of patients in the CliDR group maintained sustained remission compared with 38% in the non-CliDR group.

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May 06, 2026

Obesity Not Associated With Worse Long-Term TAR Outcomes

A long-term cohort study found that obesity was not associated with worse patient-reported outcomes or higher reoperation rates following total ankle replacement in optimized surgical candidates.

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May 05, 2026

Medical Oddities: Brain Health, Sunny-Side Up

Breakfast, bacteria, and brain wiring—small things show big implications this week.

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April 30, 2026

SSc May Be Linked to Subtle Cognitive Changes

Cross-sectional study finds domain-specific differences and higher anxiety without global impairment.

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April 23, 2026

AAO Updates HCQ Retinopathy Guidance

Updated recommendations emphasize dosing limits and screening for toxicity risk.

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April 22, 2026

Three Genes May Help Distinguish RA From OA

Machine learning and cell-line validation identify candidate biomarkers for differentiating rheumatoid arthritis vs osteoarthritis

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April 20, 2026

FDA Reshapes Drug Testing Approach

The agency outlined early regulatory actions supporting nonanimal methods, including draft guidance, artificial intelligence tools, and expanded use of human-relevant data models.

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April 20, 2026

PR Flares Linked to Future Arthritis Sites

Persistent arthritis often develops in joints affected during earlier flares

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