A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.
ACR/AAHKS guideline conditionally recommends against delaying total knee arthroplasty based solely on BMI, prompting debate among orthopedic specialists.
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Older adults who stopped antipsychotic medications after hospitalization had fewer rehospitalizations, less delirium, and lower mortality, according to a large U.S. study using real-world Medicare data.
Children with lupus nephritis had altered IgG sugar chains that impaired kidney cell metabolism, and removing those sugars reversed the injury in lab tests.
In a UK-wide analysis of nearly 2 million patients, researchers found that “a fifth of patients receiving corticosteroids accounted for over 80% of oral and inhaled corticosteroid prescribing,” highlighting concentrated use and variable treatment persistence across formulations.
A new study analyzed MRI data from over 200 participants to compare how corticosteroid and hyaluronic acid knee injections affect osteoarthritis progression, revealing distinct differences in joint deterioration over two years.