August 28, 2025

CD68/CD163 Mark Worse Outcomes in Skeletal Hodgkin Lymphoma, Study

Skeletal classic Hodgkin lymphoma shows a macrophage-rich, B-cell–poor microenvironment, with high CD68/CD163 linked to worse survival.

Conexiant

August 28, 2025

Polymerase Mutations Shape Distinct Cancer Risks

Germline mutations in POLE and POLD1 are linked to variable cancer risks, with findings highlighting mutation-specific differences that refine tumor predisposition assessment.

Conexiant

August 19, 2025

Neck Swelling, Dysphagia, and Jaw Pain: What’s Your Diagnosis?

A rare carotid artery pseudoaneurysm complicated by MRSA infection, septic arthritis, and an incidental thigh tumor challenged clinicians but was successfully treated with surgery and targeted antibiotics.

Conexiant

August 18, 2025

Early Risdiplam Use in Presymptomatic SMA Infants

Presymptomatic treatment with risdiplam was associated with improved motor development and survival without permanent ventilation in infants with spinal muscular atrophy (SMA), according to 24-month results from the phase 2 RAINBOWFISH trial published in the New England Journal of Medicine.

Conexiant

August 15, 2025

Human Cell Atlas Adds Somatic Mutation Baselines

New insights could inform studies of early cancer development in humans

The Pathologist

August 08, 2025

How Many Vacation Days Are Doctors Taking?

A survey by the American Medical Association shows a rise in physicians taking time off, reflecting an improvement in burnout rates.

Conexiant

August 07, 2025

Allogeneic Islet Transplant Shows Promise Without Immunosuppression

First-in-human trial shows genetically engineered islet cells restore insulin secretion in type 1 diabetes without triggering immune rejection.

Conexiant

August 05, 2025

What Do Patients Look for in Health Care Facilities?

An analysis of online reviews of health care facilities identified language patterns associated with positive or negative patient experiences.

Conexiant

August 04, 2025

Beta-HPV–Driven SCC Resolved After TCR Signaling Correction

Case study shows cutaneous squamous cell carcinoma linked to beta-human papillomavirus cleared following T-cell immune restoration.

Conexiant