New guidance positions GLP-1 and GLP-1/GIP therapies as frontline options for long-term weight management—with profound implications for cardiovascular outcomes, access equity, and chronic disease care.
A large Swiss study found that nighttime heart rate patterns may predict future risk for brain and psychiatric disorders, while traditional sleep structure measures were less informative.
A new systematic review and meta-analysis found that cannabis use is associated with an increased risk of major adverse cardiovascular events—including acute coronary syndrome, stroke, and cardiovascular death—based on data from more than 432 million individuals in 24 observational studies.
A human fasting study found that prolonged water-only fasting raised inflammatory and platelet activation markers, reduced amyloid beta proteins, and altered lipid and glucose metabolism, with most changes reversing after refeeding.
A 12-year study of over 4,000 adults found that poor performance on a basic sitting and rising test was strongly linked to increased risk of death from natural and cardiovascular causes.
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New research finds that heavy alcohol consumption consistently raises cardiovascular risks, while evidence for protective effects of light drinking remains inconclusive.
New research tracked subclinical carotid plaque changes over six years and found that plaques with calcification were twice as likely to develop intraplaque hemorrhage, with men showing greater risk for complex plaque progression.
A long-term U.S. study found that greater adherence to a plant-based cholesterol-lowering diet was linked to lower cardiovascular, coronary heart disease, and all-cause mortality.
Semaglutide lowered stroke risk compared to empagliflozin in adults with type 2 diabetes, though overall mortality and heart attack rates were similar between the two drugs.