Women with adverse pregnancy outcomes had higher BMI, BP, and glucose 10 years before pregnancy and persistently elevated risks up to 15 years postpartum, a new cohort study finds.
Findings indicate that while non-inferiority was not established, the reduced-dose regimen resulted in fewer bleeding complications without a marked increase in venous thromboembolism (VTE) recurrence.
Analysis of over 13,000 patients across two cohorts found that nicotinamide exposure was not associated with increased risk of major adverse cardiovascular events
The intervention did not lead to a significant reduction in the severity of PPCs compared with usual care, researchers reported in the PRIME-AIR trial.
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Patients with gout initiating urate-lowering therapy had a reduced risk of cardiovascular events when prescribed colchicine prophylaxis, researchers report.
"Although tirzepatide and semaglutide offered substantial long-term health benefits, they were not cost-effective at current net prices. Efforts to reduce the net prices of new antiobesity medications are essential to ensure equitable access to highly effective antiobesity medications."
In a national cohort study, warfarin and rivaroxaban were associated with significantly higher bleeding risks compared to apixaban in older adults with HIV and atrial fibrillation, particularly those on antiretroviral therapy.
Current prenatal supplement doses may be set well below optimal levels, as a systematic review highlights gaps in efficacy and calls for reassessment of evidence-based recommendations.