New real-world data show no significant rise in overall cancer incidence with JAK inhibitors for rheumatoid arthritis patients, though skin cancer monitoring remains important.
A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.
New criteria may aid in identifying patients with joint pain who are at high risk of developing rheumatoid arthritis, enabling earlier intervention and better trial recruitment.
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Children with lupus nephritis had altered IgG sugar chains that impaired kidney cell metabolism, and removing those sugars reversed the injury in lab tests.
In a UK-wide analysis of nearly 2 million patients, researchers found that “a fifth of patients receiving corticosteroids accounted for over 80% of oral and inhaled corticosteroid prescribing,” highlighting concentrated use and variable treatment persistence across formulations.
A large UK study found that people with multiple physical health conditions face a significantly higher risk of developing depression, with risk levels varying by type and number of conditions.