New criteria may aid in identifying patients with joint pain who are at high risk of developing rheumatoid arthritis, enabling earlier intervention and better trial recruitment.
Children with lupus nephritis had altered IgG sugar chains that impaired kidney cell metabolism, and removing those sugars reversed the injury in lab tests.
In a UK-wide analysis of nearly 2 million patients, researchers found that “a fifth of patients receiving corticosteroids accounted for over 80% of oral and inhaled corticosteroid prescribing,” highlighting concentrated use and variable treatment persistence across formulations.
In a study of 107 children with juvenile idiopathic arthritis, researchers found that one-third had growth or pubertal disturbances—often linked to disrupted hormone levels and longer disease duration.