The UK hospital study of over 80,000 patients found that certain opioids, including morphine and oxycodone, carried a higher risk of severe constipation compared with others.
A study of over 24,000 patients identified four common diagnostic paths that lead to Alzheimer’s disease, with multi-step sequences posing higher risk than single conditions and showing reproducibility in a national validation cohort.
Scientists engineered E. coli to perform a synthetic chemical reaction that enables the conversion of plastic waste into the common drug paracetamol using a non-toxic, phosphate-driven process inside living cells.
In a phase II trial reported in The Lancet Oncology, Elimova et al evaluated the efficacy and safety of zanidatamab plus chemotherapy in the first-line treatment of patients with advanced HER2-positiv...
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A large cohort study comparing methadone and buprenorphine for opioid use disorder found no significant difference in reducing illicit opioid use, but methadone showed better treatment retention after one year.
A new international consensus identifies five gynecologic conditions commonly linked with interstitial cystitis/bladder pain syndrome, urging clinicians to adopt a multidisciplinary and trauma-informed approach to care.
Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.