November 15, 2025

NGS Streamlines Clonal Detection in Plasma Cells

Research presented at AMP 2025 shows high-sensitivity sequencing may eliminate CD138 selection and speed identification of high-risk patients.

November 15, 2025

Optimizing Diagnostic Stewardship: The Clinician’s Perspective

Recommendations focus on reducing unnecessary testing and treatment while improving diagnostic accuracy.

November 15, 2025

AI Models Predict CNS Tumors From Spinal Fluid

At AMP 2025, a South Korean research team outlined a multimodal approach that integrates CSF, DNA, and MRI data to enable early, noninvasive tumor classification.

November 15, 2025

New Genetic Test Targets Rare X-Linked Movement Disorder

A targeted assay, presented at AMP 2025, identifies disease-specific TAF1 variants that standard panels often miss.

November 15, 2025

Optimizing Diagnostic Stewardship: The Lab Director’s Perspective

Programs that refine test ordering, performance, and reporting can reduce unnecessary treatments and enhance lab efficiency.

November 15, 2025

Artificial Intelligence in Health Care: The Ethical Frontier

At AMP 2025, Takunda Matose, PhD, urged pathologists to consider the limitations of big data and probabilistic reasoning to maximize AI’s benefits for clinical outcomes.

November 14, 2025

New ddPCR Test Detects Lyme Disease More Accurately

The droplet digital PCR assays, developed at Dartmouth, could improve diagnosis of Lyme disease.

November 14, 2025

Streamlining VUS Classification in Clinical Genomics

New variant classification standards and data-sharing initiatives will help laboratories and clinicians focus on actionable variants.

November 14, 2025

Michael Laposata Receives Champion for Innovation Award

At AMP’s annual meeting, the organization also honored Alexis Carter, Dara Aisner, and Lawrence Jennings for their contributions to laboratory medicine and molecular pathology.

November 14, 2025

RNA Testing Uncovers Hidden Gene Fusions in AML

Michigan team finds cryptic leukemia-defining rearrangements missed by standard cytogenetics.

November 14, 2025

Whole-Genome Sequencing Assay Detects HPV

HPV-DeepSeek identifies circulating HPV DNA, PIK3CA mutations, and integration events in pretreatment blood samples with high sensitivity and specificity.

November 14, 2025

Long-Term Data Reveal NGS Adoption Trend in LDTs

An analysis of New York State test submissions from 2010 to 2024, presented at AMP 2025, shows steady growth of NGS panels, WES, WGS, and cfDNA testing.

November 13, 2025

Old Cancer Samples Yield New Genetic Insights

A University of Chicago team demonstrates at AMP 2025 that archival pathology samples can reveal cancer’s genetic evolution.

November 13, 2025

Cancer Genomics Pioneer Honored by AMP

In her keynote lecture, Elaine R. Mardis, PhD, discussed advances in pediatric precision medicine and encouraged the expansion of data-sharing initiatives.

November 13, 2025

New AI Model Guides UTI Therapy Decisions

A predictive algorithm presented at AMP 2025 may extend the Guidance UTI workflow by delivering actionable insights before full susceptibility results are available.

November 13, 2025

Researchers Unveil Multiplex PCR for Endemic Fungi

At AMP 2025, scientists from Indiana University presented data on a rapid, highly specific PCR assay for histoplasmosis, blastomycosis, and coccidioidomycosis.