The agency did not agree with Regeneron’s proposal to add dosing intervals greater than every 16 weeks, the maximum interval currently indicated for aflibercept 8 mg injections.
“We can expect instruments to continue to improve as hardware does, and image analysis techniques to improve as more powerful machine learning algorithms are introduced,” study authors wrote.
Researchers determined that the PDS may decrease the treatment burden of frequent intravitreal injections, but further research on efficacy and safety is needed.