Higher genetic risk for schizophrenia correlated with reduced macular thickness, but the “variation is very unlikely to have an impact on visual acuity.”
The agency did not agree with Regeneron’s proposal to add dosing intervals greater than every 16 weeks, the maximum interval currently indicated for aflibercept 8 mg injections.
“We can expect instruments to continue to improve as hardware does, and image analysis techniques to improve as more powerful machine learning algorithms are introduced,” study authors wrote.