AAP released 2025 evidence-based US childhood and adolescent immunization schedule with updates for RSV, influenza, COVID-19, HPV, and meningococcal vaccines.
Presymptomatic treatment with risdiplam was associated with improved motor development and survival without permanent ventilation in infants with spinal muscular atrophy (SMA), according to 24-month results from the phase 2 RAINBOWFISH trial published in the New England Journal of Medicine.
A COVID-19 mRNA booster given during pregnancy is associated with greater transplacental antibody transfer and sustained infant antibody levels through 6 months of age.
Thai investigators test a botanical emulgel formulation to identify early safety signals related to skin irritation and allergenicity before advancing to patient trials.
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Older adults with low B-vitamin status and elevated homocysteine may have increased odds of cognitive dysfunction, and carriers of the ApoE e4 genotype faced compounded risk.
“This study builds on the emerging literature suggesting behavioral therapy may have utility as an initial therapy for the most common urinary symptoms affecting persons with PD."
Rural emergency rooms across the U.S. are increasingly staffed by physician assistants and nurse practitioners instead of physicians, raising debates over care quality, staffing shortages, and access to emergency services.