A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.
An international team developed and validated the first global classification criteria for pediatric chronic nonbacterial osteomyelitis, offering a standardized tool to improve research and diagnosis.
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A 30-year cohort study found that life-course factors—including BMI, blood pressure, and glucose—significantly influence chronic disease accumulation, but much of the risk remains unexplained.