Sotatercept reduced the composite risk of death, lung transplantation, or hospitalization for worsening pulmonary arterial hypertension by nearly 75% compared with placebo in high-risk patients in a phase III trial.
Individuals who reported a neutral level of satisfaction with their sense of belonging were approximately 3 times more likely to express an intent to leave, while those who were dissatisfied were 7 times more likely to do so, compared to individuals who were satisfied with their sense of belonging.
"Readers should not have to infer what was probably done; they should be told explicitly." This principle drives the comprehensive CONSORT 2025 update, with its 7 new checklist items aimed at improving clinical trial transparency.
UK investigators found that a shorter duration of induction dexamethasone did not reduce steroid-related toxicity, and high-dose methotrexate did not reduce CNS relapse among patients younger than age...
Large language models recommend different care based on patients' race, housing status, income level, and sexual orientation, potentially amplifying health care disparities if deployed without safeguards, researchers find.