Study shows complement activation marker C3dg, MASP-1, and MASP-3 levels before tumor necrosis factor inhibitor therapy predicted new bone formation after 2 years of follow-up among axial spondyloarthritis patients with a high risk of radiographic progression.
Despite recognizing physical and mental health advantages, rheumatologists identify evidence gaps and patient misconceptions as key obstacles — and call for RA-specific guidance.