A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.
An international team developed and validated the first global classification criteria for pediatric chronic nonbacterial osteomyelitis, offering a standardized tool to improve research and diagnosis.
A large UK study found that people with multiple physical health conditions face a significantly higher risk of developing depression, with risk levels varying by type and number of conditions.
In a study of 107 children with juvenile idiopathic arthritis, researchers found that one-third had growth or pubertal disturbances—often linked to disrupted hormone levels and longer disease duration.
Cluster 2 patients exhibited ‘a more severe form of the disease, marked with frequent serositis and haematological manifestations, renal and neurological involvement,’ and had poorer outcomes over time.
A new AI-assisted gold sensor distinguished osteoarthritis from rheumatoid arthritis with 98.1% accuracy by analyzing synovial fluid, offering a fast, noninvasive diagnostic option, researchers report.