These types of improvements are relatively common after initial approval and are the result of optimization as surgical techniques and knowledge evolve.
The agency did not agree with Regeneron’s proposal to add dosing intervals greater than every 16 weeks, the maximum interval currently indicated for aflibercept 8 mg injections.
“We can expect instruments to continue to improve as hardware does, and image analysis techniques to improve as more powerful machine learning algorithms are introduced,” study authors wrote.
Researchers determined that the PDS may decrease the treatment burden of frequent intravitreal injections, but further research on efficacy and safety is needed.
"Business owners can meet face-to-face with specialists to apply for disaster loans and access a wide range of resources to guide them through their recovery."
The lack of association between LDLs and triglycerides and AMD risk “suggests that plasma HDL specifically may play a role in progression to early and intermediate AMD.”