The TRUST trial is the first phase III randomized study to show improved progression-free survival for primary cytoreductive surgery compared with interval surgery without compromising short-term or l...
TMP-SMX is prescribed earlier in gestation than β-lactams, placing fetal exposure closer to the window of organogenesis, which may contribute to elevated malformation risk observed in first-trimester use.
Rural emergency rooms across the U.S. are increasingly staffed by physician assistants and nurse practitioners instead of physicians, raising debates over care quality, staffing shortages, and access to emergency services.
Randomized trial results showed that modified open mesh repair was as safe and effective as standard mesh repair for treating groin hernias in women, with similar recurrence and complication rates after 1 year.
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National mortality data reveal that surgeons face higher death rates than non-surgeon physicians, with cancer and external causes contributing prominently.
A Swedish cohort study of over 2.4 million births found that children born via planned cesarean section had a higher risk of developing B-cell precursor acute lymphoblastic leukemia before age 6, independent of maternal or perinatal factors.
A new review of clinical guidelines highlights consistent recommendations for diagnosing and managing placenta accreta spectrum disorders, but showed gaps in guidance for surgery, fertility counseling, and postnatal care, especially in low-resource settings.