Once used for coughs, ambroxol is being investigated for Parkinson disease dementia. A new trial shows it is safe and biologically active, though cognitive benefits remain unproven.
In a long-term cohort study, researchers found that specific retinal changes—thinner photoreceptor layers and thicker retinal pigment epithelium—were linked to a higher risk of developing amyotrophic lateral sclerosis, suggesting potential noninvasive biomarkers for early detection.
Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.
A behavioral task asking older adults to recall daily events before sleep was linked to better memory recognition the next morning, showing potential as a low-risk strategy to support cognitive health in aging and early Alzheimer’s disease.
A new study found that higher triglyceride-glucose index levels, a marker of insulin resistance, were linked to faster cognitive decline in early Alzheimer's, suggesting potential for improved risk assessment in clinical settings.
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Genetic deletion of STING in a mouse model of Alzheimer’s disease reduced amyloid plaque accumulation, suppressed neuroinflammatory responses, and improved memory, highlighting STING’s role in disease progression and potential as a therapeutic target.
A 12-year study of over 4,000 adults found that poor performance on a basic sitting and rising test was strongly linked to increased risk of death from natural and cardiovascular causes.
Older Americans are embracing vaccines—backed by new research confirming enhanced safety, disease prevention, and even a potential link to reduced dementia risk.