August 28, 2025

Polymerase Mutations Shape Distinct Cancer Risks

Germline mutations in POLE and POLD1 are linked to variable cancer risks, with findings highlighting mutation-specific differences that refine tumor predisposition assessment.

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August 27, 2025

FDA Approves LP.8.1 COVID-19 Vaccines

LP.8.1-targeted COVID-19 vaccines for adults 65 and older and higher-risk patients were approved by the US Food and Drug Administration.

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August 19, 2025

Evidence-Based Guidance for Managing Hemorrhoidal Disease

Highlights to guide treatment from lifestyle changes and phlebotonics, to office-based procedures and surgery for advanced or refractory cases.

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August 15, 2025

Indocyanine Green Angiography Shows Potential in Leak Prevention

The benefit might be in preventing grade A or B leaks, the researchers posited.

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August 15, 2025

Autoimmune Diseases Tied to Different Digestive Cancer Risks

Researchers examined celiac disease, SLE, MS, and T1D in relation to cancers of the pancreas, stomach, esophagus, small intestine, colon, rectum, liver, and gallbladder.

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August 11, 2025

FDA OKs Bioequivalent Iron Sucrose for CKD Anemia

The FDA has approved a bioequivalent iron sucrose injection for treating iron deficiency anemia in patients with chronic kidney disease.

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August 11, 2025

Ustekinumab Outperforms Vedolizumab in Pouch Crohn’s Disease

Researchers compare long-term outcomes of two biologics in managing Crohn’s disease of the pouch, focusing on clinical response, remission rates, and adverse event profiles in a real-world multicenter setting.

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August 08, 2025

INSL5 Rise Tied to Diarrhea Severity, Treatment

Circulating Insulin-like peptide 5 concentrations may reflect colonic exposure to bile acids and help stratify treatment response in patients with chronic diarrhea.

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August 05, 2025

Mailed FIT Kits Outperform Active Choice Screening

Default-mailed FIT kits sharply increased colorectal cancer screening among adults, with notable gains for college graduates and the privately insured, recent JAMA studies report.

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