ACC statement highlights semaglutide and tirzepatide as therapies associated with improved symptoms and functional capacity in patients with heart failure with preserved ejection fraction and obesity.
A new guideline recommends using lifestyle interventions as first-line treatment to prevent, manage, and potentially reverse type 2 diabetes and prediabetes, supported by extensive clinical evidence.
A large North American cohort study found that vegetarian diets were associated with lower risks of several site-specific cancers, including colorectal, stomach, breast, prostate, and lymphoproliferative cancers.
A randomized trial of 160 adults with depression and obesity found no improvement in mood symptoms from adding simvastatin to escitalopram, though the statin significantly lowered cholesterol and inflammation levels.
In a large study across 8 countries, researchers found that ultraprocessed food consumption contributed to thousands of premature deaths annually, with higher risks in countries where these foods dominate diets.
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Over 39,000 patients were followed for up to 11 years in a large national study comparing major heart event risks after gastric bypass and sleeve gastrectomy.
ACR/AAHKS guideline conditionally recommends against delaying total knee arthroplasty based solely on BMI, prompting debate among orthopedic specialists.
A large U.S. hospital database study found that postoperative urinary retention after knee replacement is rising and linked to complications, especially in older men and patients with certain health conditions.