A newly published study showed that a metabolite of paracetamol can directly block sodium channels in peripheral pain-sensing neurons, helping reduce pain without acting on the brain.
A Phase I study of intrathecal resiniferatoxin in patients with advanced cancer pain shows promising reductions in pain and opioid use, with durable effects and manageable side effects.
A large U.S. hospital database study found that postoperative urinary retention after knee replacement is rising and linked to complications, especially in older men and patients with certain health conditions.
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Scandinavian Journal of Psychology retracts study on conservatism and mental health, citing methodological flaws and biased language despite authors' objections.
A decades-long study found that adults who increased their use of sleep medications over time experienced worse hearing in late life, with the strongest associations seen in those reporting sleep disruptions.
A large UK study found that people with multiple physical health conditions face a significantly higher risk of developing depression, with risk levels varying by type and number of conditions.